MEDICATIONS TO AVOID OR USE IT WITH CAUTION IN OLDER ADULTS

Every medication has benefits and side effects. When side effects outweighs the benefits the same medication that is used to help patients can become harmful. Many older adults have multiple chronic medical problems and have to take more than one medication. Interactions between different medications can worsen the side effects.

In addition when we get older our body go through changes which causes problems with absorption , metabolism and elimination of the medication. Because of that normal dose of medication can cause overdose and cause harm. Even over the counter medications must be used with caution in older adults.

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NSAIDS (Ibuprofen, Motrin, Advil)

  • NSAIDS are used to reduce inflammation and pain.
  • When using regularly for long term it can cause ulcer and bleeding in the stomach
  • It can also increase blood pressure, worsen your kidney function and heart failure
  • If you cannot find an alternate medication, talk to your doctor to avoid harmful consequences.

Certain Diabetic Medication (Glyburide, Short acting insulin)

  • Certain diabetic medication such as Glyburide should be avoided in elderly people, since it can drop your blood sugar to a dangerously low level.
  • Low blood pressure is dangerous since it can increase the risk of fall, cause coma or even death.
  • If you are currently taking this medication, do not stop without consulting a physician. Talk to you doctor to see if there is an alternate medication to control your blood sugar.

Muscle Relaxant

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  • Certain Muscle relaxant such as cyclobenzaprine (Flexeril), methocarbamol (Robaxin), carisoprodol (Soma) can be dangerous in older patients
  • Muscle relaxants are used for pain relief
  • These medications can make you confused, cause drowsiness and increase the risk of fall in older adults
  • They can also cause constipation, dry mouth, and problems urinating

Anxiety & Sleep Medications

  • Medications such as benzodiazepine (Xanax, Valium, Ativan) and sleep aids such as Zolpidem (Ambien) and Zaleplon can cause more harm than benefit in older adults.
  • These medications can make you confused, cause drowsiness and increase the risk of fall in older adults
  • In higher doses they can even cause you stop breathing by suppressing the respiratory drive.

Anticholinergic Medications

  • Medications such as Bentyl (Dicyclomine) for Irritable bowel syndrome or certain antidepressants such as Amitriptyline needs to be used with caution in Elderly.
  • They can cause confusion, constipation, dry mouth, blurry vision, and problems urinating 

Blood Thinners

  • Blood Thinners such as Warfarin, Eliquis, Lovenox , Apixaban are used for DVT, Pulmonary embolism or for patients with Atrial Fibrillation to avoid blood clots.
  • Since Elderly people are at high risk for Fall, it can increase internal bleeding by thinning the blood.
  • If you are taking blood thinners do not stop without talking to your Doctor.
  • Talk to your Doctor to see the risks and benefits and to keep a close look on the medication level.

OVER THE counter medications (OTC)

  • OTC medications that contain antihistamin such as sleep aids , cough syrups and allergy medications can cause confusion, blurred vision, constipation, problems urinating, dry mouth and fall.

Gastrointestinal medications

  • Long term use of Proton Pump inhibitors such as Omeprazole (Prilosec), Pantoprazole (Protonix), Esomoprazole (Nexium) for Acid reflux or stomach ulcer can cause bone loss and lead to high risk of fractures

Why is having an Advance Directive for Health Care important?

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Many of us do not think about unpleasant, difficult situations when things are going well. However what we often fail to think about is that unexpected situations can happen anytime in life. As a medical professional, I have seen many young healthy adults with no medical problems get into an accident or get affected by unexpected health problems  which affects their quality of life. In such situations we might not be in a state to be able to choose or make medical decisions. I have seen patients breathing on ventilators and surviving on tube feedings for years without any quality of life

Families and loved ones often face a hard time to make a decision, especially difficult decisions.They often feel guilty to decide that its time to stop medical management even when they realise that the prognosis is poor. 

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We all have different preferences and wishes in life and having a living will or durable power of attorney helps medical professionals to respect your wishes and provide the care you wanted and it ease the burden on your loved ones. 

What is a Living Will ? 

Living will is a written document that states your wishes on how you want to be cared if you are unable to make decisions. It includes topics such as resuscitation, breathing with the help of the ventilator, tube feedings and treatments that you do not want to receive. This document helps your medical provider to decide how they should approach your treatment. Being specific as possible helps with providing your desired treatment.

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What is a Medical Power of Attorney ?

The durable power of attorney (DPOA) for health care document states the person you would want to make medical decisions for you, when you are not able to make decisions for yourself. This person should be some one you trust and they should be aware of your wishes and values. Although living will is a great way to express your wishes , it cannot cover every circumstances. This is where having a DPOA in addition to having a living will can be helpful. 

Can you change a living will?

You can cancel or make changes to your living will at any time as long as you can think rationally and can communicate your wishes. When you make changes you should sign and notarize the document to make it legal. 

Important topics to discuss in your living will

Do Not Resuscitate (DNR)

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If you happen to experience a situation where your heart stops beating or you stop breathing, medical professionals will perform cardiopulmonary resuscitation (CPR) where they will do chest compression and use medications to restart it. DNR is an order stating that you do not prefer life saving CPR or resuscitation measures. 

Do Not Intubate 

If you experience difficulty in breathing and if symptoms does not improve with less invasive measures the next step is to intubate and connect it to a machine to help you breath. Intubation is the placement of a tube into the  mouth in order to have it enter your windpipe to help you breathe. Intubation can be performed in many cases and most of them are temporary, however in some situations they can be intubated and connected to a ventilator for months to years. Some of the temporary situations include, during surgery under anesthesia, during CPR or when some one is experiencing short term loss of consciousness such as an acute intoxication. Long term intubation will be required if you have a severe lung problem or multiple comorbidities which increase the complications. You will be able to mention specific scenarios in which you do not want to be intubated ( such as long term mechanical ventilation) in your living will. 

Tube Feeding 

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If you are in a state where you are unconscious or unable to eat  Artificial nutrients and fluids can be given via tube feeding. Sometimes people can survive for years with tube feedings and mechanical ventilation. However when some one with a serious life threatening illness stops eating or drinking, it is sign that the body is beginning to stop functioning.

How can you prepare an advanced directive / Living will ?

You do not need a lawyer to fill out a living will or DPOA. Your medical doctor will be able to help you fill out your wishes and answer any questions to help you make the best decisions. Your doctors office or public health department in your state or hospitals will be able to provide you with the required form. 

Resources

A Guide to Healthy Aging

Aging is a natural process every single one of us have to go through. If the process is inevitable, why not make it a healthy and smooth ride!

Quality of life is more important than living life itself. This article will be focusing mainly on Lifestyle modifications that can improve your quality of life. Lets start to build the path to healthy aging. 

What are the lifestyle factors that contributes to a successful aging?

  • Physical Activity
  • Healthy Eating 
  • Sleep 
  • Psycho social factors
  • Substance use 

Physical Activity:


Exercise can improve your health significantly by reducing bone loss and preventing osteoporosis, reducing arthritis pain, strengthen and decrease fall and fracture risks, improve sleep and cognitive function as well as contributing to improve medical conditions such as blood pressure, Diabetes, High cholesterol and Depression. Some studies have also showed reduced risk of colon and breast cancer and death by being physically active.

It is recommended for older adults to perform at least 150 min/ week of moderate intensity exercise such as brisk walking or 75 mins/ week of vigorous intensity exercise such as jogging or running. Muscle strengthening exercises involving major muscles such as legs, hips, back , chest, shoulder and arms should be included as part of the physical activity. For those who are not active at all, even low intensity exercise such as sitting less, walking around the house while watching TV or standing more can be beneficial compared to no physical activity at all. 

Type of Exercises and its benefits 

  • Aerobic Exercise: Aerobic exercise such as walking, running, swimming, bicycling all provide cardiovascular and muscular benefits. It is always better to increase the duration of the exercise before increasing the intensity of the exercise. 
  • Resistance Training : Resistance training such as use of weights or exercise bands are associated with increase in muscle strength and muscle mass. When you first start, pick a weight which you can lift comfortably atleast 8 times. when you use weights  you should start slowly about two to three seconds to lift, hold for one second, and three to four seconds to return back to the starting position.
  • Flexibility Training : Dance exercises such as Zumba or Yoga improves flexibility and joint range of motion, endurance and muscle strength. You should slowly stretch into the preferred position and hold each stretch for about 10 to 30 seconds. 
  • Balance Training : Balance training such as Tai Chi improves balance and reduces the risk of falls and fractures.

Healthy Eating 


Malnutrition is a very common problem older adults encounter. It can be due to multiple reasons such as other medical problems affecting appetite or the ability to eat (poor dentures, etc) or Elderly negligence. Weight loss and decreased food intake is associated with increased harm and mortality in elderly. A healthy BMI in older adults is between 23- 32 kg/m2. Eating a healthy diet rich in protein, dairy, vegetables, fruits and reduced fat has shown to improve the quality of life in elderly.

Dietary supplements with vitamins are not required unless there is deficiency. Calcium and Vitamin D supplement may help with the bone health and prevent Osteoporosis. Vitamin D supplement with calcium have shown to reduce falls in people who are deficient in vitamin D, however if your vitamin D is within normal limits supplementing vitamin D will not benefit you. 

SLEEP


As we get older our duration and quality of sleep gets compromised. It is recommended to get 7- 8 hrs of sleep for adults older than 65, however 80% of older adults does not get the required amount and quality of sleep. When you do not get good sleep, your thinking, mood and functional abilities are compromised. It is important to try good sleep hygiene if you experience sleeping problems prior to trying medications, since sleeping pills have many side effects including drowsiness causing falls, affecting the breathing pattern and can even make you get addicted to them. 

What is a good sleep hygiene ? 

  • Use your bed only for sleep and sex. Do not eat or do work in bed
  • Make your bed comfortable to sleep by using the appropriate linen and pillows that make you comfortable and setting up the temperature to best suit you. 
  • Go to bed only when you are sleepy and if you cannot fall asleep for 15 – 20 mins, get up and do some light activity and then try to go back to sleep again
  • Avoid drinking caffeinated beverages in the evening and even eat your dinner early
  • If you have to wake up multiple times in the middle of the night to urinate, avoid drinking a lot of water late at night. 
  • Avoid smoking or alcohol at night
  • Increase day time activity and reduce or avoid day time naps. 
  • Try relaxation techniques such as meditation

If none of the sleep hygiene techniques help you get the sleep you need and if you have to start sleeping medication, talk to your doctor about the risks, side effects and addiction potential of each and every sleeping pills prior to making a decision.

Substance Use : 

​​Smoking is associated with reduced quality of life as well as increased mortality in older adult. Smoking can affect every single part of your body from your skin to your brain. In addition to causing multiple cancers including skin, Lungs, bladder etc and causing heart attacks and stroke , it can also affect your immune system and make you more prone to catch infections. As we get older the ability for our body to fight infections reduce and this leads to multiple hospitalizations and poor quality of life. Quitting smoking reduces the risk of death despite the age. 

Older adults with alcohol use disorder have higher rates of death due to liver failure, falls and injuries and cancer. In addition they also have poor quality of life due to the trauma and poor wound healing, increased risk of developing dementia and stroke. It is common for older adults to be on multiple medications due to other medical problems and alcohol can interact with them and affect alcohol level or drug levels causing toxicity and even death. 

Older individuals sometimes use medications that are not prescribed to them or take extra dose of medications (intentionally to increase the benefit of the medication or unintentionally due to memory problems). Due to the physiological changes that happens with aging, prescription, over the counter medications or herbal supplements tend to cause more harm in elderly when taken without a physician’s recommendation. A lot of medications and supplements are listed as a safety concern by FDA in elderly. Talk to your doctor before taking any medications or supplements.

PSYCHO-social Factors : 

Despite the medical advances and awareness there is still a stigma about depression and mental health. Older adults are at higher risk of developing major depression or depressive symptoms, however it is also most commonly missed due to contributing the symptoms to other medical problems.

Older adults have multiple risk factors to develop depression including loss of independence due to frailty or medical problems and complications from multiple medical problems. Elderly negligence or abuse is another common reason for impaired mental health.

Older men who are single have higher rates of completed suicide.  Good social support, being married , being religious are some of the factors that shows protective factor against suicide attempts. 

For those with mild depressive symptoms, improving your diet, sleep , physical and pleasure activity and social support can significantly help with depressive symptoms. If symptoms are severe your doctor can help you chose an antidepressant that is safe for you. 

Resource links: 

National Suicide Prevention Life line USA (1-800-273-8255)

Suicide Prevention Canada